Symbol
Name
ID

Pou1f1
POU domain, class 1, transcription factor 1
MGI:97588

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Human Phenotypes	Decreased response to growth hormone stimulation test	Ectopic posterior pituitary	Anterior pituitary hypoplasia	Ectopic anterior pituitary gland	Hypopituitarism	Abnormal prolactin level	Pituitary hypothyroidism
Disease(s) Associated with POU1F1
panhypopituitarism

Mouse Phenotypes

increased pituitary gland apoptosis

abnormal adenohypophysis morphology

absent lactotrophs

absent somatotrophs

decreased thyrotroph cell number

adenohypophysis hypoplasia

abnormal orientation of outer hair cell stereociliary bundles

abnormal cochlear outer hair cell morphology

cochlear outer hair cell degeneration

short cochlear outer hair cells

abnormal hair cell physiology

absent cochlear microphonics

abnormal cerebellum development

abnormal cerebellar foliation

abnormal dentate gyrus morphology

abnormal hippocampus pyramidal cell layer

abnormal hippocampus pyramidal cell morphology

decreased hippocampus pyramidal cell number

abnormal cerebellar granule layer morphology

ectopic cerebellar granule cells

Availability

Mouse Genotype

Pou1f1^dw-J/Pou1f1^dw-J

Pou1f1^dw/Pou1f1^dw

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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